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Swallow the tablets with a drink of waterYou can take Kemadrin at any time of daywith or without foodSome people find they feel less sick if they take it at meal timesThe tablet may be cut or broken in half along the break-line to divide the dose in two equal halves.

Symptoms of a procyclidine overdose include large pupilswarmdry skinflushed facefeverdry mouthfast or irregular heartbeatanxietyhallucinationsconfusionagitationhyperactivityloss of consciousnessand seizures.

Below is a text only representation of the Patient Information LeafletThe original can be viewed in PDF format using the link above.

There is no specific information available concerning the use of procyclidine hydrochloride in patients with impaired renal or hepatic functionHoweversince procyclidine is metabolised in the liver and excreted via the urine care should be exercised when administering procyclidine to patients with impairment of renal or hepatic function.

In a proportion of patients undergoing neuroleptic treatmenttardive dysknesias will occurWhile anticholinergic agents do not cause this syndromewhen given in combination with neuroleptics they may exacerbate the symptoms of tardive dyskinesia or reduce the threshold at which these symptoms appear in predisposed patientsIn such individuals subsequent adjustment of neuroleptic therapy or reduction in anticholinergic treatment should be considered.

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